No network connection when NVMe connected

When I have a NVMe SSD attached to the M.2 M key slot the device will not get network connection over ethernet. Removing the drive will restore the connection.

The NVMe SSD is a PCIe 3 x4, This model specificall in 1TB capacity https://www.teamgroupinc.com/en/product/mp33

The drive is installed unformatted and detected in BIOS.

Is this an issue? I understand the slot is PCIe 3 x2 though my understanding is any storage/peripheral will operate at lower speeds.